Wednesday, March 25, 2009

Event: Starting Companies at CU - Technology Entrepreneurship Luncheon

Join us for this lunch event kicking off CU-Boulder’s Entrepreneurship Week 2009. Meet successful tech entrepreneurs from among the CU-Boulder faculty, get an inside perspective on ION Engineering, a recent CU spinout, and learn about resources available from the Boulder Innovation Center and other CU partners.

When: Monday, April 13
Where: University Memorial Center, CU-Boulder

CU faculty/staff/grad students (no charge): 303.735.6645 or via email.
All others ($35): click here.

Presented by the CU Technology Transfer Office & the Boulder Innovation Center, and hosted by Faegre & Benson LLP.

Event: UC Denver TTO Director to Address National Tech Transfer Audience

On March 31, UC Denver TTO Director Rick Silva will be among the panelists in a national audioconference focused on effective workload management and IP assessment in tech transfer offices. To register: Invention Assessment and Triage: Improve Your TTO’s Process and Optimize Resource Allocation (via Technology Transfer Tactics).

Tuesday, March 24, 2009

Tech Spotlight: Affinity Tag-Based Purification Method for Native RNA Molecules

Production of pure native single species of RNA is necessary for a myriad of biochemistry, molecular biology, and structural biology experiments, but is time- and labor-intensive and the current denaturing method of purification is not high-throughput. Drs. Rob Batey and Jeff Kieft of the University of Colorado have developed a general method for purifying small or large quantities of any RNA oligonucleotide under nondenaturing conditions using a unique RNA affinity tag. This protocol may revolutionize RNA purification in much the same way removable affinity tags allow the rapid purification of proteins via affinity chromatography.

For more information about this technology, please contact the CU Tech Transfer Office. For more CU technologies available for licensing, please visit our Tech Explorer site.

Monday, March 23, 2009

Podcast: Dr. Heide Ford & Dr. Rui Zhao, UC Denver New Inventors of the Year

"That sort of cancer therapy is badly needed - many of the therapies available today actually target the normal cells too. That's why people get terrible side effects. So we're hoping to develop drugs that will eliminate or at least reduce the side effects significantly while inhibiting the cancer." Heide Ford and Rui Zhao, UC Denver New Inventors of the Year for 2008, discussed their current research collaboration, and offered advice for professors and researchers.

Listen to the podcast, or view a summary of this research collaboration.

Wednesday, March 18, 2009

March 2009 Newsletter Now Available

Highlights from TTO's March 2009 newsletter:

BioRelix Expands License for CU-Yale Riboswitch Technology
Yale University recently executed an agreement with BioRelix, Inc. to expand the company's commercial rights for riboswitch technology jointly developed by Robert Batey (CU-Boulder Associate Professor of Chemistry and Biochemistry) and a collaborator at Yale. BioRelix, founded in 2005 and based in New Haven, CT, was established to discover and develop novel and highly potent anti-infective compounds against pathogens resistant to currently available drugs. Riboswitches are short stretches of messenger RNAs that bind small metabolites and control genes required for the survival of many disease-causing bacteria; novel riboswitch technology may be used to defeat bacterial resistance to currently available antibiotics. The expanded license agreement adds the field of agricultural applications to the original BioRelix license.

Legislative Update: Clean Tech Research Grant Program
Earlier this year, Senator Heath and Representative Riesberg introduced Senate Bill 09-031 (PDF) in support of cleantech-related research and development, and largely modeled after HB 08-1001, the biosciences development bill. If enacted, one quarter of the funds would be directed to university cleantech proof of concept funding up to $50,000 per project matched by university funds, one quarter for matching grants to Colorado cleantech companies up to $150,000 matched by company funds, and half the funds directed to university/industry infrastructure to expand the Colorado Renewable Energy Collaboratory. In early March, the bill passed the Senate and was assigned the House Committee on Transportation & Energy.

Read the full newsletter

Tuesday, March 10, 2009

Link: BiOptix Closes $3M Series A Round, Announces New Product

RockyRadar recently featured BiOptix LLC, a company spun out of the University of Colorado at Boulder in 2004 (when it was known as AlphaSniffer). The company has developed a highly-sensitive biosensor for detection of trace amounts of bacteria, viruses, proteins, nucleic acids, antibodies and other biological and chemical agents in real-time and with minimal human intervention. (Link.)

Tech Spotlight: MicroRNA Assay Kit

Micro-RNA’s, or miRNA’s, are of increasing interest to the medical research community because of the role played by miRNA in gene regulation. This area has recently become relevant in the search for new ways of treating cancer, diabetes, and brain diseases, among others. Dr. Linda Van Dyk of the University of Colorado is developing a kit to assay miRNA’s within all steps of their maturation process in order to determine their source of origin and the potential processing enzymes used to create them. These assays would be very useful in the field of transcriptional regulation and processing of any and all RNAs. This kit could also potentially be used for diagnostics of miRNA detection (other kits are available with lower sensitivity) or where RNA processing is defective (no other assays/kits readily address this).

To read a non-confidential summary of this technology, please click the image above. For more CU technologies available for licensing, please visit our Tech Explorer site.

Tuesday, March 3, 2009

Video: Breath Test Might Be Future Of Cancer Detection

Today CBS4 (Denver) featured new research from the CU Cancer Center (UCCC) - this 'cancer breath test' could enable earlier diagnosis of lung cancer:

More information about current research programs at UCCC is available on the UCCC website.