Tuesday, August 28, 2012

Tech Spotlight: Novel Microfluidic Biodetection Platform for Equipment-Free Field Diagnostics

The ever-growing need for medical diagnostic systems in resource-limited settings is driving the development of microfluidic detection platforms. The advantages conferred by microfluidic platforms compared with their macro-scale counterparts include: lower analyte volumes, decreased reagent cost and rapid diffusion and adsorption times. Simple, standalone modes of detection for point-of-care diagnostics, particularly in resource-limited areas such as 2nd and 3rd world countries, is an area of high unmet need which micro-fluidic immunoassays can potentially fulfill; their lower analyte volumes greatly reduce the need for sterile collection materials and substantially decrease the production of biologically contaminated waste.

A research team led by Christopher Bowman of the University of Colorado has developed a novel microfluidic detection platform that utilizes polymerization-based amplification (PBA) as a means for simple detection in microfluidic systems. This capillary flow device allows for multiple modes of detection requiring little or no supplemental instrumentation (visual observation, pressure monitoring, or by redirection of fluid flow). The rapid, equipment- free nature of this approach is promising for potential deployment of point-of-care diagnostics in resource-limited settings.

To learn more, please click the image above for a non-confidential summary of this technology, or go directly to the key scientific publication. For more CU technologies available for licensing, please visit our Tech Explorer site. 

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